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Development of Adult T-cell Leukemia in a Patient with Rheumatoid Arthritis Treated with Tocilizumab


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Title: Development of Adult T-cell Leukemia in a Patient with Rheumatoid Arthritis Treated with Tocilizumab
Authors: Nakamura, Hideki / Ueki, Yukitaka / Saito, Shigeki / Horai, Yoshiro / Suzuki, Takahisa / Naoe, Tomoki / Eguchi, Katsumi / Kawakami, Atsushi
Issue Date: 1-Sep-2013
Publisher: 日本内科学会 / Japanese Society of Internal Medicine
Citation: Internal Medicine, 52(17), pp.1983-1986; 2013
Abstract: Tocilizumab (TCZ) was administered from 2004 to 2008 in a 52-year-old woman with rheumatoid arthritis (RA) refractory to methotrexate (MTX) as a clinical trial. TCZ therapy with MTX was resumed in March 2009 due to exacerbation of RA. The patient was an human T-lymphotropic virus type I (HTLV-I) carrier, and, in April 2011, a peripheral blood smear showed many atypical lymphocytes, thus leading to a diagnosis of adult T-cell leukemia (ATL). Complete remission of ATL was achieved with a standard therapeutic regimen.
Keywords: Adult T-cell leukemia / Rheumatoid arthritis / Tocilizumab
URI: http://hdl.handle.net/10069/33905
ISSN: 09182918
DOI: 10.2169/internalmedicine.52.0468
Rights: © 2013 The Japanese Society of Internal Medicine.
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/33905

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