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Guidance for peptide vaccines for the treatment of cancer

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Title: Guidance for peptide vaccines for the treatment of cancer
Authors: Yamaguchi, Yoshiyuki / Yamaue, Hiroki / Okusaka, Takuji / Okuno, Kiyotaka / Suzuki, Hiroyuki / Fujioka, Tomoaki / Otsu, Atsushi / Ohashi, Yasuo / Shimazawa, Rumiko / Nishio, Kazuto / Furuse, Junji / Minami, Hironobu / Tsunoda, Takuya / Hayashi, Yuzo / Nakamura, Yusuke
Issue Date: Jul-2014
Publisher: 日本癌学会 / Japanese Cancer Association
Citation: Cancer Science, 105(7), pp.924-931; 2014
Abstract: Recent progress in fundamental understanding of tumor immunology has opened a new avenue of cancer vaccines. Currently, the development of new cancer vaccines is a global topic and has attracted attention as one of the most important issues in Japan. There is an urgent need for the development of guidance for cancer vaccine clinical studies in order to lead to drug development. Peptide vaccines characteristically have the effect of indirectly acting against cancer through the immune system - a mechanism of action that clearly differs from anticancer drugs that exert a direct effect. Thus, the clinical development of cancer peptide vaccines should be planned and implemented based on the mechanism of action, which differs significantly from conventional anticancer drug research. The Japanese Society for Biological Therapy has created and published Guidance for peptide vaccines for the treatment of cancer as part of its mission and responsibilities towards cancer peptide vaccine development, which is now pursued globally. We welcome comments from regulators and business people as well as researchers in this area. Guidance for Peptide Cancer Vaccines.
Keywords: Cancer vaccines / Clinical study / Guidance / Non-clinical study / Peptide vaccines
URI: http://hdl.handle.net/10069/34725
ISSN: 13479032
DOI: 10.1111/cas.12443
Rights: © 2014 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association. / This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/34725

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