DSpace university logo mark
Advanced Search
Japanese | English 

NAOSITE : Nagasaki University's Academic Output SITE > School of Medicine > Articles in academic journal >

Acute exacerbation of airspace enlargement with fibrosis


File Description SizeFormat
RMCR13_19.pdf2.77 MBAdobe PDFView/Open

Title: Acute exacerbation of airspace enlargement with fibrosis
Authors: Kakugawa, Tomoyuki / Tabata, Kazuhiro / Ogawara, Daiki / Tsuchiya, Tomoshi / Hara, Shintaro / Sakamoto, Noriho / Ishimatsu, Yuji / Ashizawa, Kazuto / Nagayasu, Takeshi / Fukuoka, Junya / Kohno, Shigeru
Issue Date: 2014
Publisher: Elsevier BV
Citation: Respiratory Medicine Case Reports, 13, pp.19-23; 2014
Abstract: In 2008, Kawabata etal. described a lesion which they termed "airspace enlargement with fibrosis" that could be included on the spectrum of smoking-related interstitial lung diseases. This group also reported that patients with airspace enlargement with fibrosis but without coexisting interstitial pneumonia of another type had no acute exacerbations and favorable prognoses on clinical follow-up. Here we describe the first case, to our knowledge, of acute exacerbation of airspace enlargement with fibrosis without coexisting interstitial pneumonia of another type. An 82-year-old man was referred to our department for worsening dyspnea and new alveolar opacities on chest radiograph following left pulmonary segmentectomy (S6) for cancer. A diagnosis of acute exacerbation of airspace enlargement with fibrosis without coexisting interstitial pneumonia of other types was made, based on pathological evidence of airspace enlargement with fibrosis and organizing diffuse alveolar damage. Treatment with high-dose methylprednisolone followed by tapered oral prednisolone resulted in gradual improvement of the clinical condition and chest radiographic findings. Clinicians should be aware that patients with airspace enlargement with fibrosis may experience acute exacerbation.
Keywords: Acute exacerbation / Airspace enlargement with fibrosis / Smoking-related interstitial lung disease
URI: http://hdl.handle.net/10069/34910
ISSN: 22130071
Rights: © 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/34910

All items in NAOSITE are protected by copyright, with all rights reserved.

 

Valid XHTML 1.0! Copyright © 2006-2015 Nagasaki University Library - Feedback Powerd by DSpace