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Granular cell ameloblastoma: Case report of a particular ameloblastoma histologically resembling oncocytoma


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タイトル: Granular cell ameloblastoma: Case report of a particular ameloblastoma histologically resembling oncocytoma
著者: Matsushita, Yuki / Fujita, Shuichi / Kawasaki, Goro / Hirota, Yoshinosuke / Rokutanda, Satoshi / Yamashita, Kentaro / Yanamoto, Souichi / Ikeda, Tohru / Umeda, Masahiro
発行日: 2015年 1月
出版者: 日本病理学会 / Japanese Society of Pathology
引用: Pathology International, 65(1), pp.43-47; 2015
抄録: Granular cell ameloblastoma is classified as a histological subtype of solid/multicystic ameloblastoma. Usual granular cell ameloblastoma is histologically characterized by granular changes of stellate-like cells located in the inner portion of the epithelial follicles. Here we report a case of another type of granular cell ameloblastoma, showing predominant anastomosing double-stranded trabeculae of granular cells. This type of granular cell ameloblastoma is extremely rare, and the World Health Organization classification does not contain the entity. We tentatively termed it 'anastomosing granular cell ameloblastoma' in this report. The present case suggests the importance of differential diagnosis because the histology of 'anastomosing granular cell ameloblastoma' resembles that of salivary gland oncocytoma rather than that of usual granular cell ameloblastoma. The trabeculae observed in our case continued to the peripheral cells of a small amount of epithelial sheets of plexiform ameloblastoma, and the tumor cells were positive for CK19, which is regarded as an immunohistochemical marker of odontogenic epithelium. Similar to usual granular cell ameloblastoma, the tumor cells had CD68-positive granules. For precise diagnosis of this condition, immunohistochemistry using CK19 and CD68, as well as detailed histological observation, are recommended.
キーワード: CD68 / CK19 / Granular cell ameloblastoma / Oncocytoma
URI: http://hdl.handle.net/10069/35034
ISSN: 13205463
DOI: 10.1111/pin.12231
権利: © 2014 Japanese Society of Pathology and Wiley Publishing Asia Pty Ltd / 利用は著作権の範囲内に限られる / The definitive version is available at www.blackwell-synergy.com
資料タイプ: Journal Article
原稿種類: author
出現コレクション:040 学術雑誌論文

引用URI : http://hdl.handle.net/10069/35034

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