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Case of plasmablastic lymphoma of the sigmoid colon and literature review


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Title: Case of plasmablastic lymphoma of the sigmoid colon and literature review
Authors: Haramura, Tomoko / Haraguchi, Masashi / Irie, Junji / Ito, Shinichiro / Tokai, Hirotaka / Noda, Kazumasa / Kitajima, Masachika / Minami, Shigeki / Inoue, Keiji / Sasaki, Yuya / Oshima, Koichi / Eguchi, Susumu
Issue Date: 28-Jun-2015
Publisher: WJG Press
Citation: World Journal of Gastroenterology, 21(24), pp.7598-7603; 2015
Abstract: Plasmablastic lymphoma (PBL) is a rare form of non-Hodgkin's lymphoma that is associated with human immunodeficiency virus (HIV) infection. Although PBL is most commonly observed in the oral cavity of HIV-positive patients, it can also be observed at extra-oral sites in HIV-negative patients. This report represents an unusual case of HIV-negative PBL that occurred in the sigmoid colon. This patient had a history of systemic lupus erythematosus and an underlying immunosuppressive state from long term steroid therapy. The lymphoma cells were positive for CD138, kappa light chain restriction and Epstein-Barr virus and negative for CD20/L26, CD3, CD79a, UCHL1 (CD45RO) and cytokeratin (AE1/AE3). The patient died approximately 2 mo after the operation. In the present paper, we review cases of PBL of the colon in HIVnegative patients.
Keywords: Extra-oral site / Human immunodeficiency virus-negative / Immunosuppressive state / Plasmablastic lymphoma / Sigmoid colon
URI: http://hdl.handle.net/10069/35726
ISSN: 10079327
DOI: 10.3748/wjg.v21.i24.7598
Rights: ©2015 Baishideng Publishing Group Inc. All rights reserved. Articles published by this open-access journal are distributed under the terms of the Creative Commons Attribution-Noncommercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license.
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/35726

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