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Diffuse Alveolar Hemorrhage Emerging One Week after Starting High-dose Corticosteroid Therapy for Granulomatosis with Polyangiitis (GPA) with Systemic Lupus Erythematosus (SLE)


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Title: Diffuse Alveolar Hemorrhage Emerging One Week after Starting High-dose Corticosteroid Therapy for Granulomatosis with Polyangiitis (GPA) with Systemic Lupus Erythematosus (SLE)
Authors: Fukui, Shoichi / Iwamoto, Naoki / Tsuji, Sosuke / Umeda, Masataka / Nishino, Ayako / Nakashima, Yoshikazu / Suzuki, Takahisa / Horai, Yoshiro / Koga, Tomohiro / Kawashiri, Shin-ya / Ichinose, Kunihiro / Hirai, Yasuko / Tamai, Mami / Nakamura, Hideki / Origuchi, Tomoki / Kawakami, Atsushi
Issue Date: 15-Oct-2015
Publisher: 日本内科学会 / Japanese Society of Internal Medicine
Citation: Internal Medicine, 54(20), pp.2681-2686; 2015
Abstract: A 69-year-old man was diagnosed with granulomatosis with polyangiitis (GPA) based on the presence of skin granuloma, refractory otitis media, renal insufficiency and myeloperoxidase-antineutrophil cytoplasmic antibody positivity and slight lung opacity. He was treated with high-dose corticosteroid therapy. Despite the initial improvement of his renal function and a decrease in his C-reactive protein level, he suffered from an alveolar hemorrhage one week after the start of corticosteroid therapy. An anti-dsDNA antibody test was positive and the patient had hypocomplementemia. Elements of both GPA and systemic lupus erythematosus were thought to have affected his clinical course.
Keywords: ANCA-associated vasculitis / Diffuse alveolar hemorrhage / MDS / SLE
URI: http://hdl.handle.net/10069/36035
ISSN: 09182918
Rights: © 2015 The Japanese Society of Internal Medicine.
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/36035

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