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Multiple somatic symptoms and frailty: cross-sectional study in Japanese community-dwelling elderly people

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Title: Multiple somatic symptoms and frailty: cross-sectional study in Japanese community-dwelling elderly people
Authors: Yamanashi, Hirotomo / Shimizu, Yuji / Koyamatsu, Jun / Nobuyoshi, Masaharu / Nagayoshi, Mako / Kadota, Koichiro / Tamai, Mami / Maeda, Takahiro
Issue Date: 29-Apr-2016
Publisher: Oxford University Press
Citation: Family Practice, 33(5), pp.453-460; 2016
Abstract: Background. Physical frailty is relevant to adverse outcomes, but appropriate procedures for screening populations are lacking. We hypothesized that frailty is associated with multiple somatic symptoms because frail elderly people might have several somatic symptoms attributed to deterioration of multiple organs. Objective. To examine the association between multiple somatic symptoms and frailty. Methods. We conducted a cross-sectional study and enrolled 1818 participants aged ≥60 years from Japanese national medical check-up in 2015. Frailty status was categorized into frail, pre-frail or non-frail based on the definition of the Fried frailty phenotype model. Sixteen self-reported subjective somatic symptoms were recorded at the timing of medical check-up. Odds ratio (OR) and 95% confidence interval (CI) of frail or pre-frail were analyzed using number of somatic symptoms. Results. Out of total of 1818 subjects, 44 (2.4%) frail subjects, 635 (34.9%) pre-frail subjects and 1139 (62.7%) non-frail subjects were detected. More than two somatic symptoms were significantly associated with the frail phenotype (OR 6.20, 95% CI 2.95, 13.03, P < 0.001) and were associated with the pre-frail phenotype (OR 2.06, 95% CI 1.69, 2.51, P < 0.001). Associations remained significant after multi-adjustment for age, sex, past medical cardiovascular diseases and depressive mood The number of somatic symptoms ≥2 was thought to be the optimal cut-off point to predict frail with a sensitivity of 79.6%, specificity of 61.5%. Conclusions. Our study shows that multiple somatic symptoms are independently associated with frailty. Using more than two multiple somatic symptoms as a prescreening tool for frailty may be appropriate.
Keywords: Aging / at-risk groups / community medicine / geriatrics / medically unexplained symptoms / screening
URI: http://hdl.handle.net/10069/36923
ISSN: 02632136
DOI: 10.1093/fampra/cmw028
Rights: © The Author 2016. Published by Oxford University Press. All rights reserved. / This is a pre-copyedited, author-produced PDF of an article accepted for publication in Family Practice following peer review. The version of record Family Practice, 33(5), pp.453-460; 2016 is available online at: http://dx.doi.org/10.1093/fampra/cmw028.
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/36923

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