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Multiple somatic symptoms and frailty: cross-sectional study in Japanese community-dwelling elderly people


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タイトル: Multiple somatic symptoms and frailty: cross-sectional study in Japanese community-dwelling elderly people
著者: Yamanashi, Hirotomo / Shimizu, Yuji / Koyamatsu, Jun / Nobuyoshi, Masaharu / Nagayoshi, Mako / Kadota, Koichiro / Tamai, Mami / Maeda, Takahiro
発行日: 2016年 4月29日
出版者: Oxford University Press
引用: Family Practice, 33(5), pp.453-460; 2016
抄録: Background. Physical frailty is relevant to adverse outcomes, but appropriate procedures for screening populations are lacking. We hypothesized that frailty is associated with multiple somatic symptoms because frail elderly people might have several somatic symptoms attributed to deterioration of multiple organs. Objective. To examine the association between multiple somatic symptoms and frailty. Methods. We conducted a cross-sectional study and enrolled 1818 participants aged ≥60 years from Japanese national medical check-up in 2015. Frailty status was categorized into frail, pre-frail or non-frail based on the definition of the Fried frailty phenotype model. Sixteen self-reported subjective somatic symptoms were recorded at the timing of medical check-up. Odds ratio (OR) and 95% confidence interval (CI) of frail or pre-frail were analyzed using number of somatic symptoms. Results. Out of total of 1818 subjects, 44 (2.4%) frail subjects, 635 (34.9%) pre-frail subjects and 1139 (62.7%) non-frail subjects were detected. More than two somatic symptoms were significantly associated with the frail phenotype (OR 6.20, 95% CI 2.95, 13.03, P < 0.001) and were associated with the pre-frail phenotype (OR 2.06, 95% CI 1.69, 2.51, P < 0.001). Associations remained significant after multi-adjustment for age, sex, past medical cardiovascular diseases and depressive mood The number of somatic symptoms ≥2 was thought to be the optimal cut-off point to predict frail with a sensitivity of 79.6%, specificity of 61.5%. Conclusions. Our study shows that multiple somatic symptoms are independently associated with frailty. Using more than two multiple somatic symptoms as a prescreening tool for frailty may be appropriate.
キーワード: Aging / at-risk groups / community medicine / geriatrics / medically unexplained symptoms / screening
URI: http://hdl.handle.net/10069/36923
ISSN: 02632136
DOI: 10.1093/fampra/cmw028
権利: © The Author 2016. Published by Oxford University Press. All rights reserved. / This is a pre-copyedited, author-produced PDF of an article accepted for publication in Family Practice following peer review. The version of record Family Practice, 33(5), pp.453-460; 2016 is available online at: http://dx.doi.org/10.1093/fampra/cmw028.
資料タイプ: Journal Article
原稿種類: author
出現コレクション:110 学術雑誌論文

引用URI : http://hdl.handle.net/10069/36923

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