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Population-Based Incidence Rates of First-Ever Stroke in Central Vietnam


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Title: Population-Based Incidence Rates of First-Ever Stroke in Central Vietnam
Other Titles: 中部ベトナム地域集団における初発脳卒中の罹患率
Authors: 山梨, 啓友
Authors (alternative): Yamanashi, Hirotomo
Issue Date: 7-Dec-2016
Publisher: Public Library of Science
Citation: Nagasaki University (長崎大学), 博士(医学) (2016-12-07)
Abstract: Introduction: Stroke incidence data with methodologically acceptable design in Southeast Asia countries is limited. This study aimed to determine incidence of age-, sex- and subtype-specific first-ever stroke (FES) in Vietnam. Methods: We conducted a hospital-based retrospective study, targeting all stroke cases hospitalized at a solo-provider hospital in our study site of Nha Trang from January 2009 to December 2011 with International Classification of Diseases, 10th revision (ICD-10) codes I60-69. We calculated positive predictive values (PPVs) of each ICD-10-coded stroke by conducting a detailed case review of 190 randomly selected admissions with ICD-10 codes of I60-I69. These PPVs were then used to estimate annual incident stroke cases from the computerized database. National census data in 2009 was used as a denominator. Results: 2,693 eligible admissions were recorded during the study period. The crude annual incidence rate of total FES was 90.2 per 100,000 population (95% CI 81.1–100.2). The age-adjusted incidence of FES was 115.7 (95% CI 95.9–139.1) when adjusted to the WHO world populations. Importantly, age-adjusted intracerebral hemorrhage was as much as one third of total FES: 36.9 (95% CI 26.1–51.0). Conclusions: We found a considerable proportion of FES in Vietnam to be attributable to intracerebral hemorrhage, which is as high or exceeding levels seen in high-income countries. A high prevalence of improperly treated hypertension in Vietnam may underlie the high prevalence of intracerebral hemorrhagic stroke in this population.
Description: 長崎大学学位論文 学位記番号:博(医歯薬)甲第904号 学位授与年月日:平成28年12月7日 / Author: Hirotomo Yamanashi, Mai Quang Ngoc, Tran Van Huy, Motoi Suzuki, Akira Tsujino, Michiko Toizumi, Kensuke Takahashi, Vu Dinh Thiem, Dang Duc Anh, Nguyen Thi Hien Anh, Le Huu Tho, Takahiro Maeda, Sharon E. Cox, Lay-Myint Yoshida, Koya Ariyoshi / Citation: PLOS ONE, 11(8), e0160665; 2016
URI: http://hdl.handle.net/10069/36954
DOI: 10.1371/journal.pone.0160665
Relational Links: http://hdl.handle.net/10069/36949
Rights: © 2016 Yamanashi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Type: Thesis or Dissertation
Text Version: ETD
Appears in Collections:dissertation

Citable URI : http://hdl.handle.net/10069/36954

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