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Giant Cell Arteritis which Developed after the Administration of Granulocyte-colony Stimulating Factor for Cyclic Neutropenia


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Title: Giant Cell Arteritis which Developed after the Administration of Granulocyte-colony Stimulating Factor for Cyclic Neutropenia
Authors: Umeda, Masataka / Ikenaga, Jin / Koga, Tomohiro / Michitsuji, Toru / Shimizu, Toshimasa / Fukui, Shoichi / Nishino, Ayako / Nakasima, Yoshikazu / Kawashiri, Sin-ya / Iwamoto, Naoki / Ichinose, Kunihiro / Hirai, Yasuko / Tamai, Mami / Nakamura, Hideki / Origuchi, Tomoki / Kawakami, Atsushi
Issue Date: 15-Aug-2016
Publisher: 日本内科学会 / Japanese Society of Internal Medicine
Citation: Internal Medicine, 55(16), pp.2291-2294; 2016
Abstract: A 78-year-old woman diagnosed with cyclic neutropenia 5 years previously had been treated with recombinant granulocyte-colony stimulating factor (G-CSF). She developed fever, tenderness and distension of temporal arteries after the treatment with G-CSF. Magnetic resonance imaging and ultrasonography revealed wall thickening of the temporal arteries. She was therefore diagnosed with giant cell arteritis (GCA). Small vessel vasculitis has been reported as a complication of G-CSF. However, the development of large vessel vasculitis after G-CSF treatment is quite rare. To our knowledge, the present case is the first report of GCA suspected to be associated with coexisting cyclic neutropenia and G-CSF treatment.
Keywords: Cyclic neutropenia / Giant cell arteritis / Granulocyte-colony stimulating factor / Vasculitis
URI: http://hdl.handle.net/10069/37242
ISSN: 09182918
DOI: 10.2169/internalmedicine.55.6704
Rights: © 2016 The Japanese Society of Internal Medicine.
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/37242

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