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An Autopsy Case of Lepidic Pulmonary Metastasis from Cholangiocarcinoma


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Title: An Autopsy Case of Lepidic Pulmonary Metastasis from Cholangiocarcinoma
Authors: Nagayoshi, Yohsuke / Yamamoto, Kazuko / Hashimoto, Satoru / Hisatomi, Keiko / Doi, Seiji / Nagashima, Seiji / Kurohama, Hirokazu / Ito, Masahiro / Takazono, Takahiro / Nakamura, Shigeki / Miyazaki, Taiga / Kohno, Shigeru
Issue Date: 1-Oct-2016
Publisher: 日本内科学会 / Japanese Society of Internal Medicine
Citation: Internal Medicine, 55(19), pp.2849-2853; 2016
Abstract: We herein report the first case of pulmonary metastasis with lepidic growth that originated from cholangiocarcinoma. A 77-year-old man was admitted to our hospital due to exertional dyspnea and liver dysfunction. Computed tomography showed widespread infiltration and a ground-glass opacity in the lung and dilation of the intrahepatic bile duct. The pulmonary lesion progressed rapidly, and the patient died of respiratory failure. Cholangiocarcinoma and lepidic pulmonary metastasis were pathologically diagnosed by an autopsy. Lepidic pulmonary growth is an atypical pattern of metastasis, and immunopathological staining is useful to distinguish pulmonary metastasis from extrapulmonary cancer and primary pulmonary adenocarcinoma.
Keywords: Cholangiocarcinoma / Lepidic growth / Lung metastasis
URI: http://hdl.handle.net/10069/37297
ISSN: 09182918
DOI: 10.2169/internalmedicine.55.5972
Rights: © 2016 The Japanese Society of Internal Medicine.
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/37297

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