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Sensory defects and developmental delay among children with congenital rubella syndrome

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タイトル: Sensory defects and developmental delay among children with congenital rubella syndrome
著者: Toizumi, Michiko / Nguyen, Giang Thi Huong / Motomura, Hideki / Nguyen, Thanh Huu / Pham, Enga / Kaneko, Ken-ichi / Uematsu, Masafumi / Nguyen, Hien Anh Thi / Dang, Duc Anh / Hashizume, Masahiro / Yoshida, Lay-Myint / Moriuchi, Hiroyuki
発行日: 2017年 4月13日
出版者: Macmillan Publishers Limited
引用: Scientific Reports, 7, 46483; 2017
抄録: This study investigated the features of developmental difficulties combined with sensory defects in children with congenital rubella syndrome (CRS). Following a large rubella outbreak in Khanh Hoa Province, Vietnam, in 2011, we enrolled 41 children with CRS from September 2011 through May 2013. Fourteen participants died and six became untraceable by October 2013; the remaining 21 children were followed up from 2013 to 2015. Thirteen and seven participants had hearing and functional ophthalmological impairment, respectively. Developmental difficulties were suspected in 19 (95%) children who failed in at least one area of the Ages and Stages Questionnaire (ASQ) and/or Denver II in 2013 and/or 2015. Developmental difficulties were frequently identified in the ASQ communication domain (n = 14 in 2013) and Denver II language area (n = 13 in 2013). Seven (41%) participants were suspected of having autism spectrum disorder (ASD) in 2013 by the Modified Checklist for Autism in Toddlers. In 2015, proportions of children failing the problem-solving (62%) and personal-social (62%) domains had increased and two of 13 were diagnosed with ASD by the Childhood Autism Rating Scale, Second Edition. Developmental difficulties were suspected in most children with CRS, including autism largely combined with sensory dysfunction.
URI: http://hdl.handle.net/10069/37544
DOI: 10.1038/srep46483
権利: © 2017 The Author(s). This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
資料タイプ: Journal Article
原稿種類: publisher
出現コレクション:120 学術雑誌論文

引用URI : http://hdl.handle.net/10069/37544



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