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Detection of Zika Virus Infection in Myanmar


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Title: Detection of Zika Virus Infection in Myanmar
Authors: Ngwe Tun, Mya Myat / Moi, Meng Ling / Hasebe, Futoshi / Kyaw, Aung Kyaw / Hayasaka, Daisuke / Thant, Kyaw Zin / Thu, Hlaing Myat / Inoue, Shingo / Hmone, Saw Wut / Morita, Kouichi / Buerano, Corazon C. / Soe, Aung Min
Issue Date: Mar-2018
Publisher: American Society of Tropical Medicine and Hygiene
Citation: American Journal of Tropical Medicine and Hygiene, 98(3), pp.868-871; 2018
Abstract: Zika virus (ZIKV), an emerging mosquito-borne flavivirus, causes a dengue-like infection that has recently caught global attention. The infection, which also includes some birth defects, has been documented in the Americas, Pacific Islands, and some parts of Africa and Asia. There are no published reports on local ZIKV transmission in Myanmar. In this study, a total of 462 serum samples from patients and asymptomatic persons were collected in Myanmar from 2004 to 2017. They were analyzed for ZIKV infection by immunoglobulin M capture enzyme-linked immunosorbent assay (ELISA), immunoglobulin G indirect ELISA, neutralization test, real-time polymerase chain reaction (PCR), and conventional PCR. Our study confirmed ZIKV infection in 4.9% of patients with clinical dengue symptoms and in 8.6% of persons who were asymptomatic. This is the first report on ZIKV infection in Myanmar and it suggests the occurrence of ZIKV infection in two geographically distinct sites in this country since at least 2006.
URI: http://hdl.handle.net/10069/38261
ISSN: 00029637
DOI: 10.4269/ajtmh.17-0708
Rights: © 2018 by The American Society of Tropical Medicine and Hygiene.
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/38261

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