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Current health status and its risk factors of the Tsarang villagers living at high altitude in the Mustang district of Nepal


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タイトル: Current health status and its risk factors of the Tsarang villagers living at high altitude in the Mustang district of Nepal
著者: Koirala, Sweta / Nakano, Masayuki / Arima, Hiroaki / Takeuchi, Shouhei / Ichikawa, Tomo / Nishimura, Takayuki / Ito, Hiromu / Pandey, Basu Dev / Pandey, Kishor / Wada, Takayuki / Yamamoto, Taro
発行日: 2018年 8月29日
出版者: BioMed Central Ltd
引用: Journal of physiological anthropology, 37(1), 20; 2018
抄録: BACKGROUND: Epidemiology of noncommunicable diseases (NCDs) such as obesity and diabetes mellitus (DM) are influenced by multiple hosts and environmental factors. This study aims to investigate the prevalence of NCDs and determine their risk factors among the adults residing in an isolated village situated at a rural highland of Nepal. METHODS: A cross-sectional survey was conducted in a village located at 3570 m. Each 188 randomly selected participants of age ≥ 18 years old answered a questionnaire and took a full physical exam that included biomedical measurements of glycosylated hemoglobin (HbA1c). RESULTS: The prevalence of intermediate hyperglycemia and DM was 31.6% and 4.6% respectively, and the prevalence of hypoxemia (SpO2 < 90%) was 27.1%. A multiple logistic regression analysis for factors for the prevalence of glucose intolerance (HbA1c ≥ 6%) revealed older age (odds ratio [OR] 1.11, 95% confidence interval [CI] 1.06-1.16, for every 1 year increase) and SpO2 (OR for hypoxemia 3.58, 95% CI 1.20-10.68, vs SpO2 ≥ 90%). CONCLUSIONS: Tibetan highlanders in the remote mountainous Mustang valley of Nepal have high prevalence of impaired glucose metabolism which could be related to hypoxemia imposed by the hypoxic conditions of high altitude living.
キーワード: Cross-sectional studies / Health status / High altitude / Noncommunicable diseases / Risk factors
URI: http://hdl.handle.net/10069/38617
DOI: 10.1186/s40101-018-0181-y
権利: © The Author(s). 2018 This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
資料タイプ: Journal Article
原稿種類: publisher
出現コレクション:120 学術雑誌論文

引用URI : http://hdl.handle.net/10069/38617

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