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Reversible Cognitive Dysfunction in Elderly-onset Systemic Lupus Erythematosus, Successfully Treated with Aggressive Immunosuppressive Therapy


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タイトル: Reversible Cognitive Dysfunction in Elderly-onset Systemic Lupus Erythematosus, Successfully Treated with Aggressive Immunosuppressive Therapy
著者: Fujita, Yuya / Fukui, Shoichi / Ishida, Midori / Endo, Yushiro / Tsuji, Sosuke / Takatani, Ayuko / Igawa, Takashi / Shimizu, Toshimasa / Umeda, Masataka / Sumiyoshi, Remi / Nishino, Ayako / Koga, Tomohiro / Kawashiri, Shin-ya / Iwamoto, Naoki / Ichinose, Kunihiro / Tamai, Mami / Nakamura, Hideki / Origuchi, Tomoki / Kawakami, Atsushi
発行日: 2018年10月15日
出版者: 日本内科学会
引用: Internal medicine, 57(20), pp.3025-3028; 2018
抄録: A 70-year-old Japanese woman presented to our hospital with gait disturbance and cognitive dysfunction. Since she had arthritis, lymphopenia, hypocomplementemia, and anti-nuclear and anti-double-stranded DNA antibodies, she was diagnosed with systemic lupus erythematosus (SLE). T2-weighted magnetic resonance imaging revealed bilateral hyperintensities in the putamen. Based on her cognitive impairment, muscle rigidity, and high levels of interleukin-6 in the cerebrospinal fluid, we believed she had developed a complication of a neuropsychiatric disease and administered corticosteroids and intravenous cyclophosphamide therapy. Her cognitive function fully recovered, and her gait disturbance improved. Attending to cognitive impairment in elderly SLE patients is necessary.
キーワード: cognitive dysfunction / immunosuppressive therapy / systemic lupus erythematosus
URI: http://hdl.handle.net/10069/38686
ISSN: 09182918
DOI: 10.2169/internalmedicine.0934-18
権利: ©2018 The Japanese Society of Internal Medicine. The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/
資料タイプ: Journal Article
原稿種類: none
出現コレクション:130 学術雑誌論文

引用URI : http://hdl.handle.net/10069/38686

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