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Association of the Serum IgG level Against Periodontal Bacteria with Periodontal Status and Serum Lipid Levels


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タイトル: Association of the Serum IgG level Against Periodontal Bacteria with Periodontal Status and Serum Lipid Levels
著者: Maeda, Takahiro / Saito, Toshiyuki / Iwasaki, Takahiro / Kitamura, Masayasu / Kawasaki, Koji / Hayashida, Hideaki / Furugen, Reiko
発行日: 2018年10月10日
出版者: Dougmar Publishing Group Inc
引用: Journal of Men's Health, 14(4), pp.e11-e17; 2018
抄録: Background and Objective: Several studies have reported that serum antibodies against periodontal pathogens are related not only to periodontal status but also to systemic conditions, such as glycemic control and serum lipids. Therefore, this study examined the associations of serum IgG antibodies against periodontal pathogens with periodontal status and serum lipid levels in community dwellers. Materials and Methods: A community-based cross-sectional study of 409 subjects (140 men, 269 women) aged = 40 years who had at least 5 teeth was conducted in Goto, Japan in 2009 and 2010. Results: The serum IgG levels against Porphyromonas gingivalis were significantly associated with periodontal parameters and serum high-density lipoprotein cholesterol (HDL-C) in men. According to a multiple linear regression analysis adjusted for covariates, the serum IgG levels against P. gingivalis were inversely related to serum HDL-C (B = -0.1; P = 0.004). Conclusion: This study suggests that an elevated immune response to the periodontal pathogen is independently correlated with lower serum HDL-C level in community-dwelling men.
キーワード: HDL-cholesterol / Periodontal bacteria / Periodontitis / Serum IgG antibody
URI: http://hdl.handle.net/10069/38747
ISSN: 18756867
DOI: 10.22374/1875-6859.14.4.3
権利: © Furugen et al. This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. Copyright of articles published in all DPG titles is retained by the author(s). The author(s) grants DPG the rights to publish the article and identify itself as the original publisher. The author grants DPG exclusive commercial rights to the article. The author grants any party the rights to use the article freely for non-commercial purposes provided that the original work is properly cited.
資料タイプ: Journal Article
原稿種類: publisher
出現コレクション:130 学術雑誌論文

引用URI : http://hdl.handle.net/10069/38747

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