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Demography of sexually transmitted infections with vertical transmission


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タイトル: Demography of sexually transmitted infections with vertical transmission
著者: Ito, Hiromu / Yamamoto, Taro / Morita, Satoru
発行日: 2019年 5月 1日
出版者: Elsevier Inc.
引用: Applied Mathematics and Computation, 348, pp.363-370; 2019
抄録: Sexually transmitted infections (STIs) are an ongoing public health concern. Despite many efforts, STIs have not been eradicated. Most STIs are infected through “horizontal” sexual contact and “vertical” mother-to-child transmission. We therefore need to explore the mathematical relationship between horizontal and vertical transmissions, which is necessary for the strategic eradication of STIs. Here, we constructed a simple model to demonstrate the infection dynamics of STIs with vertical transmission. We proposed a new formulation of the basic reproduction number (R0) for STIs over generations, and showed that vertical transmission exerts a smaller effect on the R0 than horizontal transmission. We also performed agent-based simulations to validate our theoretical predictions.
キーワード: Endemic model / Mother-to-child transmission / Scale-free network / Sexually transmitted diseases (STDs) / The basic reproduction number (R0)
URI: http://hdl.handle.net/10069/38759
ISSN: 00963003
DOI: 10.1016/j.amc.2018.12.002
権利: ©2018 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/)
資料タイプ: Journal Article
原稿種類: publisher
出現コレクション:120 学術雑誌論文

引用URI : http://hdl.handle.net/10069/38759

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