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Scleroderma Renal Crisis Complicated with Thrombotic Microangiopathy Triggered by Influenza B Virus Infection


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Title: Scleroderma Renal Crisis Complicated with Thrombotic Microangiopathy Triggered by Influenza B Virus Infection
Authors: Shimizu, Toshimasa / Iwamoto, Naoki / Okamoto, Momoko / Endo, Yushiro / Tsuji, Sosuke / Takatani, Ayuko / Igawa, Takashi / Umeda, Masataka / Fukui, Shoichi / Sumiyoshi, Remi / Kitamura, Mineaki / Koga, Tomohiro / Kawashiri, Shin-ya / Ichinose, Kunihiro / Tamai, Mami / Nakamura, Hideki / Origuchi, Tomoki / Nishino, Tomoya / Kawakami, Atsushi
Issue Date: 1-Feb-2019
Publisher: 日本内科学会 / The Japanese Society of Internal Medicine
Citation: Internal medicine, 58(3), pp.441-445; 2019
Abstract: A 44-year-old Japanese man with a 14-year history of limited cutaneous systemic sclerosis (SSc) was admitted with a fever, hypertension, anemia, thrombocytopenia, and renal dysfunction. On admission, hypertension, hyperreninemia, acute renal dysfunction,hemolytic anemia, and thrombocytopenia led to the diagnosis of scleroderma renal crisis (SRC) complicated with thrombotic microangiopathy (TMA). The patient had also been infected with influenza B virus almost six days before admission. Following treatment with plasma exchange,an angiotensin-converting enzyme inhibitor, and an anti-virus agent, his general condition improved. He had no risk factors for SRC.In SSc patients, an influenza virus infection might trigger SRC complicated with TMA.
Keywords: Influenza virus / Scleroderma renal crisis / SSc / TMA
URI: http://hdl.handle.net/10069/38862
ISSN: 09182918
DOI: 10.2169/internalmedicine.1441-18
Rights: Ⓒ 2019 The Japanese Society of Internal Medicine. The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).  
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/38862

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