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The effect of self-sampled HPV testing on participation in cervical cancer screening on a remote island


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Title: The effect of self-sampled HPV testing on participation in cervical cancer screening on a remote island
Other Titles: 離島における子宮頸がん検診の受診率向上に向けた自己採取HPV検査導入の有効性に関する研究
Authors: 山﨑, 真紀子
Authors (alternative): Yamasaki, Makiko
Issue Date: 5-Dec-2018
Publisher: 長崎大学医学部
Citation: Nagasaki University (長崎大学), 博士(医学) (2018-12-05)
Abstract: Aim: Self-sampling devices for oncogenic human papillomavirus (HPV) testing may be useful for improving participation in cervical cancer screening. The aim of this study was to investigate the effects of HPV self-sampling devices for non-attenders, who have not participated in regular cervical cancer screening. Methods: To determine whether HPV self-sampling devices improve participation in cervical cancer screening on a remote island, non-attenders aged 20–49 years were included in this study. Participation was defined as returning a self-sampling device and/or participating in a conventional cytology-based cervical cancer screening. From April 2014 to May 2015, written informed consent for participation in this study was obtained from 249 of 2,986 non-attenders in the Goto Islands and randomly assigned to the “re-call” group (n=124) or the self-sampling group (n=125). Results: The participation (by returning the HPV self-sampling device and/or attending a cervical cancer screening) rate was 12.1% (n = 15) in the “re-call” group and 76.0% (n = 95) in the self-sampling group. Only 50% of HPV-positive women (n=5) underwent cytological testing, and abnormal cytological findings were detected in two cases. For these two patients with abnormal cytology, carcinoma in situ was detected and treated. Conclusions: Offering HPV self-sampling devices may improve participation in cervical cancer screening on remote islands in Japan.
Description: 長崎大学学位論文 学位記番号:博(医歯薬)甲第1105号 学位授与年月日:平成30年12月5日 / Author: Makiko Yamasaki, Shuhei Abe, Kiyonori Miura, Hideaki Masuzaki / Citation: Acta Medica Nagasakiensia, 62(2), pp.55-61; 2019
Keywords: carcinoma in situ / cervical cancer screening / non-attenders / participation rate / HPV / self-sampling
URI: http://hdl.handle.net/10069/38872
Relational Links: http://hdl.handle.net/10069/38741
Rights: (C) 2018 Nagasaki University School of Medicine
Type: Thesis or Dissertation
Text Version: ETD
Appears in Collections:dissertation

Citable URI : http://hdl.handle.net/10069/38872

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