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Frequent unregulated use of antibiotics in rural Cambodian infants

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Title: Frequent unregulated use of antibiotics in rural Cambodian infants
Authors: Cox, Sharon E / Iwamoto, Azusa / Matsui, Mitsuaki / Taing, Bunsreng / Tung, Rathavy / Miyazaki, Asuka
Issue Date: 20-Apr-2020
Publisher: Oxford University Press
Citation: Transactions of the Royal Society of Tropical Medicine and Hygiene, 114(6), pp.401-407; 2020
Abstract: BACKGROUND: Despite a high prevalence of antibiotic resistance in Cambodia, few studies have assessed health-seeking behaviour and the use of antibiotics by caregivers of young children in Cambodia. METHODS: We conducted a cross-sectional survey of infants <12 months of age and their caregivers, assessing the frequency of reported illness, common symptoms and associated health-seeking behaviour through structured questionnaires administered by trained fieldworkers at a home visit. In a subset of these participants, ages 4-8 months with no acute malnutrition, we conducted a 3-month surveillance with fortnightly home visits. RESULTS: Of 149 infants (ages 1-11 months, 54.4% male) enrolled in the cross-sectional study, 76 (51.4%) reported symptoms of diarrhoea, fever or cough in the previous 14 d, with associated use of antibiotics reported in 22 (14.8%) infants. In 47 infants enrolled in the longitudinal surveillance, there were 141 reported episodes of illness in 44 (94%) infants with 21 infants (45%) reported to have received antibiotics in 32/141 (22.7%) episodes. Amoxicillin was the most commonly reported antibiotic in both surveys (68% [40/59 episodes reporting the use of antibiotics]). CONCLUSIONS: Antibiotic usage is high in this population and appears to be occurring largely outside of the formal healthcare system.
Keywords: Cambodia / antibiotics / infants
URI: http://hdl.handle.net/10069/40053
ISSN: 00359203
DOI: 10.1093/trstmh/traa020
Rights: © The Author(s) 2020. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, providedthe original work is properly cited.
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/40053

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