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豚人工免疫による日本脳炎ウイルス保毒蚊の増幅抑制に関する研究予報


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タイトル: 豚人工免疫による日本脳炎ウイルス保毒蚊の増幅抑制に関する研究予報
その他のタイトル: Effects of Immunization of Swine upon the Ecological Cycle of Japanese Encephalitis Virus : I. Preliminary Report
著者: 高橋, 克巳 / 松尾, 礼三 / 熊, 正昭 / 馬場, 純一 / 野口, 英太郎 / 田口, 末春 / 松本, 熙 / 合沢, 龍信 / 浜里, 徳雄
著者(別表記) : Takahashi, Katsumi / Matsuo, Reizo / Kuma, Masaaki / Baba, Junichi / Noguchi, Hidetaro / Taguchi, Sueharu / Matsumoto, Hiroshi / Aizawa, Tatsunobu / Hamasato, Tokuo
発行日: 1968年11月20日
出版者: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
引用: 熱帯医学 Tropical medicine 10(3). p181-194, 1968
抄録: Though it has been demonstrated that swine are major natural source of amplification of mosquito infection with Japanese encephalitis(JE) virus particularly in early summer, there is no radical and practical countermeasure to control the epidemic of Japanese encephalitis. However, it should be worthy to examine that swine vaccination against JE virus before epidemic season might be effective for the control of vector mosquitoes which would be infected with JE virus. Following this conceptation, after swine vaccination in spring, mosquito infection with JE virus had been investigated in 1966 and 1967 at Karako hamlet located and separated from other villages in the south district of Nagasaki prefecture, comparing with that in neighbouring Aino village. The results were obtained as follows: 1) In 1966, at Karako hamlet, the swine except over-summered ones had been immunized with inactivated vaccine with high potancy at 2 or 3 times during from March to April. At the beginning of May, hemagglutination inhibition antibody had developed at the titer of 1:10 or more in the sera of 70 per cent of total tested. 2) In Karako hamlet, the isolation rate of JE virus from mosquitoes of Culex tritaeniorhynchus had remarkably lower than that in Aino village and no peak of the rate could be found throughout the epidemic season in 1966. On the contrary in Aino village, the pattern of virus isolation from mosquitoes in epidemic season had presented the typical hyperbolic curve as described in the previous paper. 3) In 1967, swine vaccination did not carried out in Karako hamlet and Aino village too. In this case, the essential differences of isolation pattern of JE virus from mosquitoes could not be found in both villages. 4) From the results above described, it seemed to be suggested that swine vaccination is to control the vector Imosquitoes infected with JE virus. However, the examination should be made at strictly separated places such as island. Furthermore the higher potential vaccine for swine should be applied.
URI: http://hdl.handle.net/10069/4040
ISSN: 03855643
資料タイプ: Departmental Bulletin Paper
出現コレクション:第10巻 第3号

引用URI : http://hdl.handle.net/10069/4040

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