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ECHOウイルス11型の性状に関する研究 : I. Plaque変異ウイルスについて(ECHOウイルス11型の性状に関する研究)


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Title: ECHOウイルス11型の性状に関する研究 : I. Plaque変異ウイルスについて(ECHOウイルス11型の性状に関する研究)
Other Titles: Studies on Mutants of ECHO Virus Type 11 : I. Characteristics of Plaque Variant Viruses (Studies on Mutants of ECHO Virus Type 11)
Authors: 陳, 境津
Authors (alternative): Chen, Jeng Jieng
Issue Date: 30-Jun-1971
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 13(2). p45-52, 1971
Abstract: Gregory strain of ECHO virus type 11 contained two types of plaque variant viruses. The distinguishable characteristics between them are presented as follows: the properties of large plaque (Lp) variant virus are that 4.0 to 6.0 mm in diameter of plaque size, less titer of the virus produced in infected HeLa cells than that of small plaque (Sp) variant virus, poor adsorption onto HeLa cells, weak cytopathogenicity, thermolability at 50℃, sensitivity to the interferon-like substance prepared from culture fluids of Sp virus carrier HeLa cells and to be easily neutralized with anti-Lp and anti-Sp rabbit serum are observed. On the other hand, the peculiarity of the Sp variant virus is that 0.5 to 1.0 mm in diameter of plaque size, high adsorption onto HeLa cells, intensive cytopathogenicity, thermostability at 50℃, weak sensitivity to the interferon-like substance and remarkable breakthrough-phenomenon are demonstrated.
URI: http://hdl.handle.net/10069/4089
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 13, No. 2

Citable URI : http://hdl.handle.net/10069/4089

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