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Title: ムコール菌症の4剖検例報告
Other Titles: Histopathological Studies of Phycomycosis Four Case Reports
Authors: 関根, 一郎
Authors (alternative): Sekine, Ichiro
Issue Date: 30-Dec-1972
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 14(4). p176-185, 1972
Abstract: Histopathologic studies of the four autopsy cases of phycomycosis were performed. It has been postulated that phycomycosis may have a remarkably rapid course, death may occur within a few days after the first symptoms and relatively acute changes such as rapid intracapillary growing of the fungus, thrombosis and infarction rather than reactive inflammatory cell infiltration or specific granulation tissue are prominent. And also, such acute, non-reactive changes are characteristic feature of the mycosis, because it commonly follows on other severe, debilitating diseases, especially in their last stage and the period of infection of the mycosis may be too short to occur any reactive changes in the patients. In two cases out of four which we examined, on the contrary, the clinical courses were considered to be prolonged, more than two months. These cases showed nonspecific granulation tissue proliferation with foreign body giant cells, histologically. In phycomycosis, the toxicity of organisms may be mild and tissue destruction due to the fungus growing usually do not occur and one of the main changes is multiple embolism. Therefore, it appears that reactive inflammatory cell infiltration and/or specific granulation tissue proliferation are less prominent and delayed to grow than any other fungus or bacterial infections. The cases being reported in this paper are as follows: Case 1 31 yrs. female Acute myeloid leukemia Case 2 14 yrs. male Acute myeloid leukemia Case 3 26 yrs. male Acute myeloid leukemia Case 4 55 yrs. male Carcinoma of the stomach
URI: http://hdl.handle.net/10069/4123
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 14, No. 4

Citable URI : http://hdl.handle.net/10069/4123

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