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肝生検によるカラ・アザールの病理形態


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Title: 肝生検によるカラ・アザールの病理形態
Other Titles: Histopathology of Liver Biopsy of Kala-azar
Authors: 山下, 裕人 / 千馬, 正敬 / 板倉, 英世 / 浅井, 利勝 / 中林, 敏夫 / 中富, 昌夫 / 原, 耕平
Authors (alternative): Yamashita, Hiroto / Senba, Masachika / Itakura, Hideyo / Asai, Toshikatsu / Nakabayashi, Toshio / Nakatomi, Masao / Hara, Kohei
Issue Date: 30-Nov-1979
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 21(3). p127-130, 1979
Abstract: Histopathological study of Kala-azar using liver biopsy was done. The patient was a 19-year-old African of Trukana tribe. He had emaciation, hepato-splenomegaly and hyperglobulinemia. Microscopic examination of biopsy specimen of the liver revealed marked infiltration of plasma cells, lymphocytes and macrophages mainly in the portal areas. Among these cells, plasma cells were most prominent. Therefore, the plasma cell is likely to be one of the main reactive cells in Kala-azar. Leishman-Donovan bodies were found mainly in macrophages in portal areas and in Kupper's cells in lobules. However, they could also be seen in parenchymal cells in some parts of the liver. Characteristic intracellular organelles of the protozoa, such as nucleus, kinetoplast and axoneme were found by electron microscopic examination. Therefore, this protozoa was confirmed to be in the amastigote stage. Histopathological differences of Kala-azar from chronic active hepatitis and histoplasmosis were also discussed.
URI: http://hdl.handle.net/10069/4258
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 21, No. 3

Citable URI : http://hdl.handle.net/10069/4258

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