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多形性誘導培地におけるコレラ菌の毒素産生について


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Title: 多形性誘導培地におけるコレラ菌の毒素産生について
Other Titles: Toxin Production and Morphological Changes of Vibrio cholerae in the Medium for Inducing Pleomorphism
Authors: 岩永, 正明 / 内藤, 達郎
Authors (alternative): Iwanaga, Masaaki / Naito, Tatsuro
Issue Date: 28-Mar-1980
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 22(1). p61-68, 1980
Abstract: ブイヨンに白糖,硫酸マグネシウム,グリシンをそれぞれ10%, 0.2%, 1%に加えてコレラ菌を37℃で培養すると,速やかに多形性となり,本来の桿状姿は殆どみられなくなった.この形態はコレラ菌569B株をSyncase mediumで30℃振盪培養した時のものと同様であったが, Syncase mediumでみられたような毒素産生は全くみられなかった.またSyncase mediumでは多形性を示さなかったコレラ菌K-25株もこの培地では多形性を示したが,毒素の産生はみられなかった.従って,コレラ菌の毒素産生は必ずしも多形性と一致するものではないといえる. / Pleomorphism in Vibrio cholerae was induced by glycine under hypertonic conditions. Under these conditions, almost all of the organisms converted from a rod shape to a round shape with pleomorphism. However, RPHA (reversed passive hemagglutination assay) and rabbit skin reaction tests failed to detect toxin in the medium. These morphological changes were similar to those seen in cultures with shaking syncase medium at 30℃, in which the organisms released a large amount of toxin. It is suggested that this kind of morphology does not always accompany toxin excretion.
URI: http://hdl.handle.net/10069/4274
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 22, No. 1

Citable URI : http://hdl.handle.net/10069/4274

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