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いわゆるBuruli ulcerの一例


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Title: いわゆるBuruli ulcerの一例
Other Titles: A Histopathological Study of the so-called Buruli ulcer
Authors: 山下, 裕人 / 千馬, 正敬 / 板倉, 英世
Authors (alternative): Yamashita, Hiroto / Senba, Masachika / Itakura, Hideyo
Issue Date: 30-Oct-1980
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 22(3). p161-166, 1980
Abstract: A histopathological study of the so-called "Buruli ulcer" was reported. The patient was a 10-year-old African boy in Kenya suffering from ulcer formation. The ulcer was 10cm in diameter and located over the left hip. It was undermined and covered by overhanged epithelia at the ulcer edge. There was edema or lytic change in the dermis which formed gaps between the epidermis and dermis in adjacent regions. Microscopically, inflammatory cells infiltration, granulation tissue, fibrosis, and several epitheloid cell tubercles were observed at the base of the ulcer. In the ulcer edge, active reactions of Langhans' giant cells, epitheloid cell tubercles, lymphocytes, and plasma cells were seen. In the surrounding non-ulcerated areas, zonal acellular necrosis, which was pathognomonic findings of "Buruli ulcer", was found in the lower dermis and subcutaneous fat tissues. It seemed that the original site of the zonal necrosis was subcutaneous fat tissues. Neither bacteria nor fungi were found in our case.
URI: http://hdl.handle.net/10069/4283
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 22, No. 3

Citable URI : http://hdl.handle.net/10069/4283

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