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NAOSITE : Nagasaki University's Academic Output SITE > Institute of Tropical Medicine > Bulletin > Tropical medicine > Volume 26, No. 1 >

Dirofilaria immitisミクロフィラリア感染マウスに於けるDiethylcarbamazine投与時のIHA titerの変動

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Title: Dirofilaria immitisミクロフィラリア感染マウスに於けるDiethylcarbamazine投与時のIHA titerの変動
Other Titles: The Change of the Indirect Hemagglutination Titers in Mice Infected with Dirofilaria immitis Microfilariae following the Administration of Diethylcarbamazine
Authors: TRANGAY, Maria de Lourdes Aracely LUJAN / 坂本, 信 / 嶋田, 雅暁 / 木村, 英作 / 青木, 克己
Authors (alternative): Trangay, Maria De Lourdes Aracely Lujan / Sakamoto, Makoto / Shimada, Masaaki / Kimura, Eisaku / Aoki, Yoshiki
Issue Date: 31-Mar-1984
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 26(1). p11-15, 1984
Abstract: Dirofilaria immitisミクロフィラリア30,000隻を6匹のICRマウスのソ径部皮下に毎週1回10週間接種後DEC 300mg/kgで3日間治療した.DEC投与前のIHA titerの最高値は1:240であったが投与後1週目よりtiterは上昇し始め4週目には全てのマウスが最高値(4匹は1:960,2匹は1:480)を示し6週までの観察期間ではtiterは最高値を維持した. / About 30,000 microfilariae of D. immitis were inoculated into ICR mice subcutaneously. The mice were injected with DEC at 300mg/kg/day for 3 consecutive days, then the IHA test was carried out until 6 weeks after DEC treatment. Before DEC treatment, the IHA titers in two of six mice was 1:240 and those in the other four was 1:120. One week after DEC treatment, the IHA titer began to rise in most mice and at 4 weeks, those in all mice reached maximum. During the observation period, the maximum titers in four of six mice was 1:960 and those in the remaining two was 1:480.
URI: http://hdl.handle.net/10069/4371
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 26, No. 1

Citable URI : http://hdl.handle.net/10069/4371

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