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近交系ハムスターにおけるB. pahangiの研究 : 2. CBNハムスター及び数種のげっ歯類に対する感染幼虫の睾丸内接種

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Title: 近交系ハムスターにおけるB. pahangiの研究 : 2. CBNハムスター及び数種のげっ歯類に対する感染幼虫の睾丸内接種
Other Titles: Studies on Brugia pahangi in Inbred Hamsters : 2. The intratesticular inoculation of infective larvae into CBN hamsters and some other rodents
Authors: 木村, 英作 / 重野, 鎮義 / 坂本, 信 / 嶋田, 雅暁 / 青木, 克己 / Waikagul, Jitra
Authors (alternative): Kimura, Eisaku / Shigeno, Shizugi / Sakamoto, Makoto / Shimada, Masaaki / Aoki, Yoshiki / Waikagul, Jitra
Issue Date: 30-Jun-1984
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 26(2). p51-56, 1984
Abstract: Brugia pahangi感染幼虫を睾丸内接種法を用いて近交系CBNハムスター,スナネズミ,ICRマウスに感染させ,その後30-70日の間に動物を剖検して発育期幼虫の回収を試みた.CBNハムスターでは平均74.3%という高い回収率が得られた.そのうち63.5%は感染幼虫を接種された睾丸より得られたものである.接種された睾丸及びその周囲組織は一塊として容易に切除されるが,この二つの部位を合せると全回収虫体の90%が得られることになり,従来多大の労力を要した幼虫の回収作業が著しく簡略化される.スナネズミの場合には,睾丸外への幼虫移動がすみやかであり,またマウスでは幼虫の回収率がきわめて低く睾丸内接種法による利点は無かった. / Inbred CBN hamsters, Mongolian jirds and ICR mice were infected with B. pahangi by intratesticular inoculation of infective larvae. The animals were sacrificed within 30-70 days postinoculation and developing stages of larvae were recovered. In CBN hamsters, the average recovery rate was as high as 74.3%, of which 63.5% were obtained from the inoculated testes. When the inoculated testis and its peritesticular tissues, which can be excised en masse, are combined, 90% of the recovery were from these two sites. The results obtained from jirds and mice were not encouraging due to the escape of larvae from the testis or the poor recovery rate.
URI: http://hdl.handle.net/10069/4377
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 26, No. 2

Citable URI : http://hdl.handle.net/10069/4377

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