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長崎県におけるつつが虫病の血清疫学的研究


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Title: 長崎県におけるつつが虫病の血清疫学的研究
Other Titles: Seroepidemiological Investigation on Rickettstia Tsutsugamushi in Nagasaki Prefecture
Authors: 鈴木, 寛 / 福本, 美枝 / 松本, 慶蔵 / 松尾, 礼三 / 鍬塚, 真 / 嘉勢, 洋一
Authors (alternative): Suzuki, Hiroshi / Fukumoto, Yoshie / Matsumoto, Keizo / Matsuo, Reizo / Kuwazuka, Makoto / Kase, Youichi
Issue Date: 28-Dec-1984
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 26(4). p157-164, 1984
Abstract: 長崎県においては,昭和57年に5例のつつが虫病患者が始めて報告された.そこで,和58年冬期に長崎県各地における住民に対するリケッチア・ツツガムシ抗体をImmune Peroxidase法(Gilliam strain)により測定した.対象地区は,長崎市(120名),島原市(120名),大瀬戸町(50名),福江市(50名),若松町(44名)で,対象数は総計314名であった.長崎県全体としての陽性率は5.1%で,地域別にみた陽性率の最高は大瀬戸町の8.0%,最低は島原市の2.0%であった.陽性者の抗体は,1:20~1:80に分布していた.尚,陽性率の地域差および年代差はみられなかった.しかし,これらの成績から,本県においてもリケッチア・ツツガムシに感染した野ネズミが既に存在していることが示唆された. / Levels of serum IgG antibody to Rickettsia tsutsugamushi were determined by the immune peroxidase method on 314 healthy inhabitants in Nagasaki prefecture. Of the 314 inhabitants 120 were from Nagasaki city, 50 from Shimabara city, 50 from Fukue city, 50 from Oseto town and 44 from Wakamatsu town. Mean positive rate in Nagasaki prefecture was 5.1 per cent. The highest positive rate was 8.0 per cent from Oseto own and the lowest one was 2.0 per cent from Shimabara city. However these results were not significantly different according to the x^2-test. The level of antibody in positive cases ranged from 1:20 to 1:80 in serum dilution and the positive rate at each decade ranged from 4.0 per cent at the 4th decade to 15.0 per cent at the 3rd decade. These results were, however, not significant when checked by x^2-test. These results indicate that wild rodents had been already infected by Rickettsia tsutsugamushi in some areas before we found clinical cases of Rickettsia tsutsugamushi in Nagasaki prefecture.
URI: http://hdl.handle.net/10069/4390
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 26, No. 4

Citable URI : http://hdl.handle.net/10069/4390

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