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Title: 1983年ケニア・ビクトリア湖周辺におけるコレラの疫学的観察
Other Titles: Epidemiological Observation of Cholera in Rural Kenya in 1983
Authors: 江原, 雅彦 / 渡邊, 繁徳 / 一瀬, 休生 / 霜鳥, 翔一 / Siongok, Timoth K. arap / Muriith, Kibue Ali Ahamed / Sang, Florence Chepkimoi
Authors (alternative): Ehara, Masahiko / Watanabe, Shigenori / Ichinose, Yoshio / Shimodori, Shoichi / Shiongok, Timoth K. Arap / Muriith, Kibue Ali Ahamed / Sang, Florence Chepkimoi
Issue Date: 28-Dec-1985
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 27(4). p229-240, 1985
Abstract: Homa Bay地区病院のコレラ検査室で調べられた約17,000検体のうち再検例を除く,1,301検体が陽性者で,うち入院者788名,健康保菌者513名であった.コレラ感染率は13~19歳の男性に最も少なく,15~39歳の女性に最も高かった.流行は3月と7月にみられ,いずれも乾期の終わりで雨期に入る直前であった.月別・年齢別にみると,3月は20~39歳,7月は13~19歳に最も多くみられた.地区別にみると,KarachuonyoとKanyadaに患者は集中していた.致命率は9%と高く,発展途上国のもつ,共通の背景があるように思われた.家族内感染は161例に認められ,他は散発例であった.薬剤感受性については,1982年に多剤耐性株が若干認められたが,1983年のほとんどが耐性株であり,O/129にも耐性を示した.耐生パターンはタンザニア分離株のそれとも異なっており,コレラ菌の土着性を思わせた.この疫学調査で最も重要なことはコレラは再感染がほとんど認められないということであった。即ち,有効なワクチン開発の可能性が大であることを示唆している. / More than 17,000 rectal swab specimens were examined for Vibrio cholerae Ol at Cholera Laboratory in Homa Bay District Hospital. Out of these specimens, 1,301 cases were bacteriologically cholera-positive excluding repeated specimens. The number of admitted cases and healthy carriers were 788 and 513 respectively. Infection rate of cholera was lowest in the age-group, 13-19 of male. It was highest in female of childbearing age-group (15-39). Monthly variation of cholera-positive cases showed two peaks in March and July, closely correlated with the dry season. Monthly variation of cholera by age-group also showed two peaks in March and July. The former peak was formed by the age-group of 20-39 and the latter was by 13-19. High infection rate was found in Karachuonyo and Kanyada. The mortality of the admitted cases was 9%. One hundred and sixty-one cases were thought to be caused by family contacts, however most of the others were sporadic cases. Tetracycline resistant strains were isolated in 1982 even in Kenya, though the number was small. Most of the strains isolated in 1983 were resistant to multiple antimicrobial agents as well as O/129 which is a vibriostatic agent.
URI: http://hdl.handle.net/10069/4424
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 27, No. 4

Citable URI : http://hdl.handle.net/10069/4424

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