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Title: ケニアにおける病原性大腸菌感染
Other Titles: Enteropathogenic Escherichia coli (EPEC) Infection in Kenya
Authors: 江原, 雅彦 / 渡邊, 繁徳 / 一瀬, 休生 / 霜鳥, 翔一 / M., KIBUE ALI A. / SANG, F. C.
Authors (alternative): Ehara, Masahiko / Watanabe, Shigenori / Ichinose, Yoshio / Shimodori, Shoichi / Muriith, Kibue Ali Ahamed / Sang, Florence Chepkimoi
Issue Date: 31-Mar-1986
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 28(1). p35-44>, 1986
Abstract: 病原性大腸菌(EPEC)の保菌者の動態を把握するため,Kwale地区の住民約400人から約3ヵ月間隔で3回,検体(Rectal swab)を収集し,菌検索を行った.各検体からE. coliを3 colonyずつ拾って市販のEPEC抗血清(デンカ生研)による凝集で,型別を行った.毎回の本菌陽性率は同程度で約20%であった.そのうち毎回陽性であったのは1例のみで,2回陽性は19例であったが,いずれも異なった血清型を示していた.即ち,同一血清型株の再感染は認められず,病原性大腸菌の場合にもlong term immunityを考慮する必要があることを示唆するものとみられた.sample提供者は全て健康であった.また,Cholera survey, C. jejuni survey等で集めたE. coliも全て凝集を行い,約2,000人からのデータをまとめてEPECの保菌率,型別,ETEC検出率,性差,年齢差,地域差,健康者と下痢患者間の検出率の相異などに検討を加えた結果,いずれの場合にも感染率に有意の差は認められなかった. / About two thousands of rectal swab-specimens were examined for enteropathogenic Escherichia coli (EPEC) in rural area in Kenya in 1983 by using 28 of monovalent antisera which were commercially available. According to the results obtained, there was no significant difference in the isolation rate of EPEC strains (about 20%) between diarrheal patients and healthy individuals. No marked difference was also observed in the isolation rate by age-group as well as by sex. The most dominantly isolated strain of EPEC was O27: K+ which is a well known enterotoxigenic Escherichia coli (ETEC). Most of EPEC strains isolated were identified as ETEC and some were enteroinvasive Escherichia coli (EIEC) by serotyping alone. In the three surveys with 2-3 months interval carried out for the fixed populations, the same serotype as found in the former survey was not isolated from the same individual. Although nineteen cases showed EPEC positive more than twice during the surveys. The isolation rate of EPEC in food-handlers working at the hotels in the South Coast was 20%, although they were healthy without diarrhea.
URI: http://hdl.handle.net/10069/4435
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 28, No. 1

Citable URI : http://hdl.handle.net/10069/4435

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