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オリゴヌクレオチドフィンガープリント法による日本脳炎(JE)ウイルスの分子疫学的研究


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タイトル: オリゴヌクレオチドフィンガープリント法による日本脳炎(JE)ウイルスの分子疫学的研究
その他のタイトル: Oligonucleotide Fingerprint Analysis on Japanese Encephalitis (JE) Virus Strains of Different Geographic Origins
著者: 堀, 博之
著者(別表記) : Hori, Hiroyuki
発行日: 1986年 9月30日
出版者: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
引用: 熱帯医学 Tropical medicine 28(3). p179-190, 1986
抄録: Genetic variation in Japanese encephalitis virus isolates from various geographic areas was examined by oligonucleotide fingerprint of the 42S genome RNA. Isolates in the same geographic areas and in the same years were very similar but differed from those in other areas or in different years in the same areas. Japanese isolates were rather similar to each other and similarity between strains was greater as the years of isolations were closer. Recent isolates from Thailand and Vietnam were similar to each other, however, they were quite different from Japanese isolates. Two Taiwan isolates in 1981 with high similarity to each other were also quite different from Thai and Vietnamese isolates, although one of them showed relative closeness to recent Japanese isolates. From these results, it was presumed that mutations and selections of JE virus genome would have progressed independently in geographically distant areas. Nakayama (Japan, 1935) and Peking-1 (China, 1949) strains were rather similar, suggesting that early Japanese strains may have some relationships to early Chinese strains.
URI: http://hdl.handle.net/10069/4449
ISSN: 03855643
資料タイプ: Departmental Bulletin Paper
出現コレクション:第28巻 第3号

引用URI : http://hdl.handle.net/10069/4449

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