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高温におけるポリオウイルスの安定化に対する塩酸濃度の効果


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Title: 高温におけるポリオウイルスの安定化に対する塩酸濃度の効果
Other Titles: Effect of Hydrochloric Acid Concentration on the Stabilization of Poliovirus at High Temperature
Authors: Srivastava, Ashok Kumar / Koza, Jiri / Matyasova, Irena
Authors (alternative): Srivastava, Ashok Kumar / Koza, Jiri / Matyasova, Irena
Issue Date: 31-Mar-1987
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 29(1). p55-56, 1987
Abstract: ポリオウィルス弱毒株Sabin 1型、LSc 2abと3型Leon 12a_1bをpH 1.3から3.0の間の種々の濃度の塩酸溶液中で50℃,15分間処理してその安定性を検討したところ,ヒトの胃酸濃度に相当するpH 2.0で最も安定であるという結果が得られた. / Attenuated poliovirus Sabin strains type 1 LSc 2ab and type 3 Leon 12a_1b have been stabilized in different concentration of hydrocholoric acid (HCl) between pH 1.3 to 3.0 at 50℃ for 15 minutes. These strains were temperature stable at pH 2.0 which corresponds to the concentration of HCl in human stomach.
URI: http://hdl.handle.net/10069/4488
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 29, No. 1

Citable URI : http://hdl.handle.net/10069/4488

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