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Title: 長崎県の2島におけるトキソプラスマ感染症に関する血清疫学的研究
Other Titles: Seroepidemiology of Toxoplasma Infection in Two Islands of Nagasaki by ELISA
Authors: 鈴木, 寛 / 麻生, 卓郎 / 山本, 由美子 / 松本, 慶蔵
Authors (alternative): Suzuki, Hiroshi / Aso, Takuro / Yamamoto, Yumiko / Matsumoto, Keizo
Issue Date: 30-Jun-1988
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 30(2). p129-139, 1988
Abstract: 長崎県において,生活環境ならびに生活様式が近似している平島(283名)と江ノ島(270名)在住の6-79才の健康な住民を対象として,特異性IgG抗体を酵素抗体法にて測定することによりトキソプラスマ感染症に関する血清疫学的研究を行った.抗体陽性率は平島(44.2%)が江ノ島(34.1%)より有意に高値であった.地区別陽性率の差異は平島(7地区)では認められたが,江ノ島(3地区)では認められなかった.年代別の抗体陽転率は平島では15-35才(2.8%)で高いのに比して,江の島では65才以上の年代で高値であったが,加令に伴う抗体陽性率は平島では段階的,江ノ島では直線的上昇傾向を示した. 1年間隔での抗体の4倍以上の有意の変動検出率は平島(5.8%)と江ノ島(2.6%)で異なっていた.これらの成績はトキソプラスマの感染様態が2つの島の住民で異なっていることを示唆した. / In Hirashima Island and Enoshima Island in Nagasaki prefecture, where human ecology and environmental conditions are the same, Toxoplasma infection of appatently healthy inhabitants aged from 6 to 79 years was investigated by determining speficic IgG antibody to T. gondii by ELISA. In 1985 serum specimens were collected from 283 and 270 inhabitants in Hirashima and Enoshima Islands, respectively. In 1986 serum samples were again collected from 196 and 205 inhabitants whose sera were collected in 1985 in the same islands. The overall positive rate of Toxoplasma infection was higher in Hirashima Island (44.2%) than in Enoshima Island (34.1%) and the difference was statistically significant. The positive rates at 7 areas in Hirashima Island were different from area to area, while at 3 areas in Enoshima Island the positive rates were similar. The calculated annual incidence rates were similar in Hirashima Island (0.9%) and in Enoshima Island (0.8%). The positive rate increased with a linear fashion with advancing age in Enoshima Island and in a stepwise fashion in Hirashima Island. Furthermore, the calculated annual new infection risk was high at the age of 15 to 35 years (2.8%) in Hirashima Island and at the age of 65 to 75 years (3.8%) in Enoshima Island. At an interval of 1 year, seroconversion (0.9%) was detected among inhabitants in Hirashima Island only. Rising rate of the antibody level was 5.8% in Hirashima Island and 2.6% in Enoshima Island. These results indicate that the prevalence pattern of T. gondii is different between the two Islands.
URI: http://hdl.handle.net/10069/4521
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 30, No. 2

Citable URI : http://hdl.handle.net/10069/4521

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