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Comparative Amino Acid Sequences of Dengue Viruses

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タイトル: Comparative Amino Acid Sequences of Dengue Viruses
著者: Haishi, Shozo / Tanaka, Mariko / Igarashi, Akira
発行日: 1990年 6月30日
出版者: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
引用: 熱帯医学 Tropical medicine 32(2). p81-87, 1990
抄録: Amino acid (AA) sequences of 4 serotype of dengue viruses deduced from their nucleotide (nt) sequences of genomic RNA were analyzed for each genome segment and each stretch of 10 AA residues. Precursor of membrane protein (pM), and 4 nonstructural proteins (NS1, NS3, NS4B, NS5) were highly conserved, while another nonstructural protein (NS2A) was least conserved among 5 strains of dengue viruses. When homology was compared among heterotypic viruses, type 1 and type 3 dengue viruses showed close relationships, while type 4 dengue virus was relatively remote from other types. When AA sequences were compared for each 10 AA residues, some highly conserved as well as least conserved domains were identified. Significance of these findings for diagnostic virology and epidemiological survey was discussed.
URI: http://hdl.handle.net/10069/4566
ISSN: 03855643
資料タイプ: Departmental Bulletin Paper
出現コレクション:第32巻 第2号

引用URI : http://hdl.handle.net/10069/4566



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