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Effect of Praziquantel on Hatching of Schistosoma haematobium Eggs


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Title: Effect of Praziquantel on Hatching of Schistosoma haematobium Eggs
Authors: Katsumata, Tatsuya / Migwi, D. K. / Muhoho, N. D. / Kimura, Eisaku / Shimada, Masaaki / Aoki, Yoshiki
Issue Date: 7-May-1993
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 35(1). p17-21, 1993
Abstract: The hatchability of Schistosoma haematobium eggs excreted by patients treated with praziquantel (PZQ) was examined. The rate of hatching of the eggs excreted by the patients before treatment was 90.1%. The rates of hatching of the eggs excreted by the patients 3 hr, 24 hr and 48 hr after treatment were 25.5%, 19.2% and 29.9% respectively. In vivo PZQ inhibits the hatching of S. haematobium eggs. The result of in vivo experiment was strongly supported by the results of the in vitro experiments. The hatching of the eggs exposed to PZQ at a concentration of 0.1μg/ml for one hour in vitro was inhibited.
URI: http://hdl.handle.net/10069/4619
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 35, No. 1

Citable URI : http://hdl.handle.net/10069/4619

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