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Malignant Mesodermal Mixed Tumor of the Bladder : A Case Report


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Title: Malignant Mesodermal Mixed Tumor of the Bladder : A Case Report
Authors: Mwinyimtwana, Ahmed Makata / Toriyama, Kan / Eto, Hideaki / Itakura, Hideyo / Iwamoto, Masanori
Issue Date: 27-Dec-1993
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 35(3). p111-118, 1993
Abstract: We report an autopsy case of malignant mesodermal mixed tumor of the urinary bladder of a 67 year old male. He had been admitted to Kita Hospital under the diagnosis of Alzheimer's disease since 1979. His dementia aggravated and he was confined to bed in 1985. While in the hospital, he developed hematuria and calculi and necrotic materials were sometimes noticed in his urine. Although the CT scan and intravenous urography revealed left hydronephrosis and vesical lithiasis, urinary cytological studies showed no remarkable changes. At the beginning of September 1992, he was found to have a child's fist-sized tumor in his left lower abdominal cavity, which was diagnosed as a bladder tumor and left renal pelvic tumor. The tumor grew rapidly and reached a child's head-size within 3 months. Several cytological examinations of his urine were performed, but all showed negative for malignancy. There was no tumor response against anti-cancer chemotherapy and he died on November 22, 1992. Autopsy revealed a bulky tumor mass which occupied the whole lower abdominal cavity. Histologically, the tumor was composed of an epithelial element of well differentiated squamous cell carcinoma and a non-epithelial element of rhabdomyosarcoma. The cross striations in rhabdomyosarcoma cells were clearly stained by PTAH. Immunohistochemically, rhabdomyosarcoma cells were positively stained by Desmin and partially by Vimentin. Therefore we diagnosed this tumor as malignant mesodermal mixed tumor of the urinary bladder.
URI: http://hdl.handle.net/10069/4630
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 35, No. 3

Citable URI : http://hdl.handle.net/10069/4630

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