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Brown Adipose Tissue in Amyotrophic Lateral Sclerosis

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タイトル: Brown Adipose Tissue in Amyotrophic Lateral Sclerosis
著者: Ito, Masahiro / Matsuzaki, Sumihiro / Yamaguchi, Eiichiro / Nakashima, Masahiro / Nakayama, Toshiyuki / Naito, Shinji / Sekine, Ichiro
発行日: 1994年10月30日
出版者: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
引用: 熱帯医学 Tropical medicine 36(2). p43-49, 1994
抄録: The prevalence of brown adipose tissue (BAT) in the periadrenal adipose tissue was studied in 20 autopsy cases of amyotrophic lateral sclerosis (ALS). In 19 of 20 cases, the periadrenal BAT in focal or diffuse distribution was observed. Histometry of BAT revealed average occupancy rates of 21.6% and 4.2% in ALS and age-matched control cases, respectively (p<0.01). Since emaciation and chronic hypoxia in those ALS patients were most likely related to severe muscle wasting and respiratory involvement, it is speculated that an increase in BAT occupancy rates may be secondary to altered thermogenesis which was augmented by chronic hypoxia.
URI: http://hdl.handle.net/10069/4670
ISSN: 03855643
資料タイプ: Departmental Bulletin Paper
出現コレクション:第36巻 第2号

引用URI : http://hdl.handle.net/10069/4670



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