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Clinical Manifestations and Treatment of Dengue Hemorrhagic Fever (DHF) by 13 Years Experience, More Than 10,000 Cases


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Title: Clinical Manifestations and Treatment of Dengue Hemorrhagic Fever (DHF) by 13 Years Experience, More Than 10,000 Cases
Authors: Kanungkit, Somyos / Nimnakorn, Pisit / Morita, Kouichi / Igarashi, Akira
Issue Date: 28-Dec-1994
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 36(3). p93-101, 1994
Abstract: Clinical manifestations and treatment on dengue hemorrhagic fever (DHF) were summarized based on 13 years experience of the first author at the Pediatric Department, Nakorn Phanom Provincial Hospital, Thailand. DHF is an acute febrile disease, characterized by hemoconcentration, thrombocytopenia, and coagulopathy. The underlying mechanism of increased vascular permeability, leads to hemoconcentration, hypovolemic shock, metabolic abnormalities, then disseminated intravascular coagulation (DIC), if not properly treated. Direct cause of death in DHF is either circulatory failure or massive hemorrhage. Therefore, DHF case management should be directed to correct determination of the stage and grade of the disease, and prescribe proper recipes, such as intravenous infusion and blood transfusion.
URI: http://hdl.handle.net/10069/4677
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 36, No. 3

Citable URI : http://hdl.handle.net/10069/4677

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