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Arbovirus Infections in Pilot Areas in Laos

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Title: Arbovirus Infections in Pilot Areas in Laos
Authors: Makino, Yoshihiro / Saito, Mika / Phommasack, Bounlay / Vongxay, Phonsavanh / Kanemura, Kazumi / Pothawan, Traykhouane / Bounsou / Insisiengmay, Sithat / Sompaw / Fukunaga, Toshihiko
Issue Date: 31-Mar-1995
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 36(4). p131-139, 1995
Abstract: Since 1993, virological and seroepidemiological survey of arbovirus infections was conducted in pilot areas in Laos under the World Health Organization-Japan International Cooperation Agency-Laos trilateral Primary Health Care Project. Human sera were obtained at the laboratory in Khammouane Provincial Hospital, and at Sok Yai village in Vientiane Municipality, and antibodies to Japanese encephalitis (JE), dengue (DEN) and chikungunya (CHIK) viruses were assayed by neutralization test. The sera were classified according to the age groups. In Khammouane area, antibody-positive rates to DEN-1, 2, and 3 reached high (over 90%) by 11-15 years old and kept high thereafter. Antibody-positive rates to DEN-4 and JE increased with age and reached over 50% by 21-30 and 31-40 years old, respectively. In Sok Yai area, antibody-positive rates to DEN-2 and 3 were over 50% in all age groups. The positive rate of DEN-1 antibody reached 50% by 11-15 years old and increased with age. Although DEN-4 and JE antibody-positive rates fluctuated among age groups, they tended to increase with age. JE antibody survey in swine sera indicated that the JE virus was active during the rainy season. Positive rate of CHIK antibody tended to increase with age and reached over 50% in older age groups. These results indicate that DEN-1, 2, and 3 viruses are circulating more frequently in these areas. DEN-4, JE and CHIK viruses also exist with less activity. In terms of the primary health care for the prevention and control of arbovirus infections, the project team conducted health education and environmental sanitation in Sok Yai village. They also organized several training courses on the diagnosis and treatment of JE and DEN for junior doctors, health workers, and laboratory technicians.
URI: http://hdl.handle.net/10069/4683
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 36, No. 4

Citable URI : http://hdl.handle.net/10069/4683

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