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A Comparative Study of Liver Cell Regenerative Activity between Primary Biliary Cirrhosis, Alcoholic Cirrhosis, Hepatitic Cirrhosis, and Hepatocellular Carcinoma using Figure Analysis


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タイトル: A Comparative Study of Liver Cell Regenerative Activity between Primary Biliary Cirrhosis, Alcoholic Cirrhosis, Hepatitic Cirrhosis, and Hepatocellular Carcinoma using Figure Analysis
著者: Rahman, Sheikh Mizanur / Itakura, Hideyo / Motoda, Akira
発行日: 1995年 6月23日
出版者: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
引用: 熱帯医学 Tropical medicine 37(1). p13-20, 1995
抄録: Liver cell regeneration which is a prominent pathological feature in cirrhosis of the liver was examined histopathologically and by figure analysis using immage analyser. Liver cell regenerative changes in liver biopsies of primary biliary cirrhosis (PBC), alcoholic cirrhosis, hepatitic cirrhosis, and hepatocellular carcinoma (HCC) were compared. In PBC, regenerative features of liver cells were mild in degree. In alcoholic cirrhosis, regenerative liver cells were less prominent than in hepatitic cirrhosis. In hepatitic cirrhosis, regenerative liver cell nodules were well developed, showing remarkable pleomorphism of liver cell nuclei and expansive arrangement of liver cell cords. Cellular and structural atypia were observed in some parts of regenerative nodules. These results suggest that a possibility of occurring HCC is much more prominent in hepatitic cirrhosis than in PBC or alcoholic cirrhosis, because developement of liver cell regeneration is most remarkable in hepatitic cirrhosis.
URI: http://hdl.handle.net/10069/4699
ISSN: 03855643
資料タイプ: Departmental Bulletin Paper
出現コレクション:第37巻 第1号

引用URI : http://hdl.handle.net/10069/4699

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