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Antifilarial Effect of a Plant Acacia auriculiformis on Canine Dirofilariasis

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Title: Antifilarial Effect of a Plant Acacia auriculiformis on Canine Dirofilariasis
Authors: Chakraborty, Tanushree / Sinhababu, Santi Prasad / Sukul, Nirmal Chandra
Issue Date: 23-Jun-1995
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 37(1). p35-37, 1995
Abstract: An ethanolic extract was obtained from the funicles of Acacia auriculiformis. The extract was allowed to evaporate and the residue thus obtained was administered orally to 4 pariah dogs naturally infected with Dirofilaria immitis at 150mg/kg/day for 45 days. The treatment resulted in 98% and 99% reduction in microfilarial density on day 45 and day 75, respectively following the onset of treatment. Microfilarial density rose gradually and the level of reduction in the sampling on day 165 was 59%. No toxic effect in the form of a change in movement, body weight and temperature was observed in the treated dogs. The prolonged maintenance of reduced level of microfilarial density may be ascribed to the partial elimination of adult worms.
URI: http://hdl.handle.net/10069/4702
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 37, No. 1

Citable URI : http://hdl.handle.net/10069/4702

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