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Transmission of Japanese Encephalitis (JE) Virus in Gia Luong District, Ha Bac Province, Vietnam, After Je Vaccination, 1993-1994


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Title: Transmission of Japanese Encephalitis (JE) Virus in Gia Luong District, Ha Bac Province, Vietnam, After Je Vaccination, 1993-1994
Authors: Nga, Phan Thi / Phuong, Le Kim / Nam, Vu Sinh / Yen, Nguyen Thu / Tien, Tran Van / Lien, Huynh Phuong
Issue Date: 29-Mar-1996
Publisher: 長崎大学熱帯医学研究所 / Institute of Tropical Medicine, Nagasaki University
Citation: 熱帯医学 Tropical medicine 37(4). p129-134, 1996
Abstract: A total of 15,183 children under 10 years old (37% of target population) was immunized with JE vaccine in Gia Luong District, Ha Bac Province, Vietnam, in 1993 to 1994. JE virus transmission was investigated by swine antibody survey and virus isolation from field mosquitoes. By the hemagglutination inhibition (HI) test, 73-90% of swine were antibody positive all year round, with high geometric mean titer (GMT) of 92.67-95.14 in May and June. By suckling mouse brain inoculation, 6 JE virus strains were isolated from Culex tritaeniorhynchus and Cx. vishuni, as well as laboratory reared F1 from field-caught Cx. tritaeniorhynchus. Serodiganosis by IgM-capture ELISA (MAC-ELISA) carried out on 60 of 85 clinical encephalitis cases detected 43 positives (71.66%). All these serologically confirmed JE cases had not been vaccinated. The results supported the vaccine efficacy to prevent overt JE.
URI: http://hdl.handle.net/10069/4713
ISSN: 03855643
Type: Departmental Bulletin Paper
Appears in Collections:Volume 37, No. 4

Citable URI : http://hdl.handle.net/10069/4713

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