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糸状虫症の化學療法に関する研究 : 第1報 Diethylcarbamazineの体液中濃度の測定法について


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Title: 糸状虫症の化學療法に関する研究 : 第1報 Diethylcarbamazineの体液中濃度の測定法について
Other Titles: Studies on the Chemotherapy of Filariasis due to Wuchereria Bancrofti : 1st Report: Determination of diethylcarbamazine in body fluids
Authors: 藤巻, 博教
Authors (alternative): Fujimaki, Hironori
Issue Date: 25-Nov-1955
Citation: 長崎大学風土病研究所業績 4. p.1596-1598, 1955
Abstract: Diethylcarbamazine (1-diethylcarbamyl-4-methyl-piperazine hydrochioride) was introduced by Hewitt and co-workers (1947) and applied to filariasis caused by Litomosoides carinii and Dirofilana immitis. They described that this drug was also remarkable effective on microfilaria bancrofti. M. Lubran (1950) described that it was possible to estimate the diethylcarbamazine in body fluids by an application of the general method for the determination of organic bases described by Brodie and Udenfriend (1945). The author found possible to estimate the small amount of diethylcarbamazine in body fluids through the electrospectrophotometer to modificate the Lubran's method. Experiments were done to pursue the relation between the effects and the level in body fluids in administration of various dosis. In this report the method was introduced.
URI: http://hdl.handle.net/10069/4887
Type: Departmental Bulletin Paper
Appears in Collections:Issue 4

Citable URI : http://hdl.handle.net/10069/4887

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