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糸状虫症の化學療法に関する研究 : 第1報 Diethylcarbamazineの体液中濃度の測定法について

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タイトル: 糸状虫症の化學療法に関する研究 : 第1報 Diethylcarbamazineの体液中濃度の測定法について
その他のタイトル: Studies on the Chemotherapy of Filariasis due to Wuchereria Bancrofti : 1st Report: Determination of diethylcarbamazine in body fluids
著者: 藤巻, 博教
著者(別表記) : Fujimaki, Hironori
発行日: 1955年11月25日
引用: 長崎大学風土病研究所業績 4. p.1596-1598, 1955
抄録: Diethylcarbamazine (1-diethylcarbamyl-4-methyl-piperazine hydrochioride) was introduced by Hewitt and co-workers (1947) and applied to filariasis caused by Litomosoides carinii and Dirofilana immitis. They described that this drug was also remarkable effective on microfilaria bancrofti. M. Lubran (1950) described that it was possible to estimate the diethylcarbamazine in body fluids by an application of the general method for the determination of organic bases described by Brodie and Udenfriend (1945). The author found possible to estimate the small amount of diethylcarbamazine in body fluids through the electrospectrophotometer to modificate the Lubran's method. Experiments were done to pursue the relation between the effects and the level in body fluids in administration of various dosis. In this report the method was introduced.
URI: http://hdl.handle.net/10069/4887
資料タイプ: Departmental Bulletin Paper

引用URI : http://hdl.handle.net/10069/4887



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