|
NAOSITE : Nagasaki University's Academic Output SITE >
120 熱帯医学研究所 >
120 学術雑誌論文 >
THE EFFECT OF MEDICATION ON QUESTIONNAIRE ANALYSIS OF CHILDREN WITH SCHISTOSOMA MANSONI INFECTION IN TANZANIA
タイトル: | THE EFFECT OF MEDICATION ON QUESTIONNAIRE ANALYSIS OF CHILDREN WITH SCHISTOSOMA MANSONI INFECTION IN TANZANIA |
著者: | Kisu, Tomoko / Shiratori, Kiyoshi / francis callyst / Ataka, Yuji / Kaneda, Eiko / elisonguo ngomuo / richard j. shayo / Shimada, Masaaki |
発行日: | 2005年12月 |
出版者: | 日本熱帯医学会 / The Japanese Society of Tropical Medicine |
引用: | Tropical Medicine and Health Vol. 33 No. 3, 2005, pp. 143-152 |
抄録: | The effect of mass treatment on questionnaire results in the diagnosis of schistosomiasis mansoni was examined in 267 school children in an endemic area of Tanzania by Kato-Katz analysis of fecal specimens. The questionnaire asked for information about self-diagnosis, abdominal symptoms, blood in stools, history of wild water contact, stool examination and medication for schistosomiasis, and knowledge of the disease. A logistic regression analysis disclosed a significant association between schistosomiasis and diarrhea (p ? 0.007; odds ratio, 32.0; confidence interval, 2.5 - 403.3) and abdominal enlargement (p ? 0.003; odds ratio, 15.2; confidence interval, 2.6 - 90.1) among 61 children who had no history of medication for schistosomiasis. The sensitivity and specificity of the model were 86% and 64%, respectively. In contrast, no significant correlation was observed either for the 116 treated children, or for all the 267 children after the mass treatment. We conclude, therefore, that for children who had no history of medication for schistosomiasis, the questionnaire for abdominal manifestations provides reliable information on S. mansoni infection. However, once a child takes medication, the questionnaire becomes unreliable. This observation suggests that immunomodulation by anti-schistosomiasis drugs that kill adult worms exerts an effect on the appearance of abdominal manifestations and might explain the ambiguity of clinical symptoms in chronically infested patients, except in terminal cases. Further studies are required to develop a simple, rapid and cost-effective diagnostic method for monitoring S. mansoni infection after medication in local areas without resort to laboratory-based identification of schistosomiasis. |
キーワード: | Schistosoma mansoni / self-diagnosis / selective mass treatment / Tanzania |
URI: | http://hdl.handle.net/10069/5665 |
ISSN: | 13488945 |
関連リンク : | http://www.jstage.jst.go.jp/article/tmh/33/3/143/_pdf/-char/ja/ |
権利: | Copyright(c) 2005 by The Japanese Society of Tropical Medicine |
資料タイプ: | Journal Article |
原稿種類: | publisher |
出現コレクション: | 120 学術雑誌論文
|
引用URI :
http://hdl.handle.net/10069/5665
|
このリポジトリに保管されている文献はすべて著作権により保護されています。 印刷やダウンロード等データの複製は、調査研究・教育または学習を目的とする場合に限定されます。
|