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Photodecomposition and Bioconcentration of a Bisphenol A Metabolite in Medaka, Oryzias latipes


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Title: Photodecomposition and Bioconcentration of a Bisphenol A Metabolite in Medaka, Oryzias latipes
Authors: Takao, Yuji / Shimazu, Miki / Kohra, Shinya / Nagae, Masaki / Ishibashi, Yasuhiro / Tominaga, Nobuaki / Ishibashi, Hiroshi / Yoshihara, Shinich / Arizono, Koji
Issue Date: Dec-2004
Publisher: Pharmaceutical Society of Japan
Citation: Journal of Health Science v.50(6) p.576-580, 2004
Abstract: Exposure experiments in medaka and photodecomposition tests were performed using a metabolite of bisphenol A [4-methyl-2,4-bis(p-hydroxyphenyl)-pent-1-ene; MBP], the solubility limit of which is 42 mg/l of water. Three adult medaka were kept in a 2 l glass beaker at 25 ± 1°C for 4 days. The LC50 for 96 hr was > 1000 ppb. The measured average MBP concentration in the breeding water (nominal concentration of 100 ppb) was 49.2 ppb. The average concentration in the whole bodies of medaka after 4 days was 1.92 mg/g-wet body, and the bioconcentration factor (BCF) of MBP was calculated to be 39.0. MBP in water and acetone was decomposed very easily, with about 98% of the MBP being decomposed after several hours under sunlight. MBP was also decomposed after 48 hr of illumination under a white fluorescent lamp.
Keywords: bisphenol A metabolite / bioconcentration factor / photodecomposition
URI: http://hdl.handle.net/10069/8366
ISSN: 13449702
DOI: 10.1248/jhs.50.576
Relational Links: http://dx.doi.org/10.1248/jhs.50.576
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/8366

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