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Iridoids and Anthraquinones from the Malaysian Medicinal Plant, Saprosma scortechinii (Rubiaceae)


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Title: Iridoids and Anthraquinones from the Malaysian Medicinal Plant, Saprosma scortechinii (Rubiaceae)
Authors: Ling, Sui-Kiong / Komorita, Akiko / Tanaka, Takashi / Fujioka, Toshihiro / Mihashi, Kunihide / Kouno, Isao
Issue Date: Aug-2002
Publisher: Pharmaceutical Society of Japan
Citation: Chemical & Pharmaceutical Bulletin v.50(8) p.1035-1040, 2002
Abstract: A further investigation of the leaves and stems of Saprosma scortechinii afforded 13 compounds, of which 10 are new compounds. These were elucidated as the bis-iridoid glucosides, saprosmosides G (1) and H (2), the iridoid glucoside, 6-O-epi-acetylscandoside (3), and the anthraquinones, 1-methoxy-3-hydroxy-2-carbomethoxy-9,10-anthraquinone (4), 1-methoxy-3-hydroxy-2-carbomethoxy-9,10-anthraquinone 3-O-β-primeveroside (5), 1,3-dihydroxy-2-carbomethoxy-9,10-anthraquinone 3-O-β-primeveroside (6), 1,3,6-trihydroxy-2-methoxymethyl-9,10-anthraquinone (7), 1-methoxy-3,6-dihydroxy-2-hydroxymethyl-9,10-anthraquinone (8), 1,3,6-trihydroxy-2-hydroxymethyl-9,10-anthraquinone 3-O-β-primeveroside (9), and 3,6-dihydroxy-2-hydroxymethyl-9,10-anthraquinone (10). Structure assignments for all compounds were established by means of mass and NMR spectroscopies, chemical methods, and comparison with published data. The new anthraquinones were derivatives of munjistin and lucidin.
Keywords: Saprosma scortechinii / Rubiaceae / bis-iridoid glucoside / sulfur-containing iridoid / anthraquinone
URI: http://hdl.handle.net/10069/8404
ISSN: 00092363
DOI: 10.1248/cpb.50.1035
PubMed ID: 12192133
Relational Links: http://dx.doi.org/10.1248/cpb.50.1035
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/8404

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