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A Comparison of Hepatic Resection and Ablative Therapy regarding the Survival of Hepatocellular Carcinoma Patients in Nagasaki


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Title: A Comparison of Hepatic Resection and Ablative Therapy regarding the Survival of Hepatocellular Carcinoma Patients in Nagasaki
Authors: Nanashima, Atsushi / Yamaguchi, Hiroyuki / Omagari, Katsuhisa / Nakazaki, Takayuki / Aritomi, Tomoyuki / Hatano, Kazuhiko / Sumida, Yorihisa / Shibasaki, Shinichi / Ide, Noboru / Nakagoe, Tohru / Nagayasu, Takeshi
Issue Date: Sep-2004
Citation: Acta medica Nagasakiensia. 2004, 49(3), p.87-91
Abstract: To identify the effect of local treatments for hepatocellular carcinoma (HCC) in our associated institutes in Nagasaki prefecture, we performed a comparative study of hepatic resection and local ablative therapies, including alcohol injection, microwave coagulation and radio-frequency ablation. We examined the patient demographics, outcomes and tumor-free and overall survival between a hepatectomy group (n=210) and a local ablative therapy group (n=52). In the ablative therapy group, there were significantly more patients with cirrhosis and poorer hepatic function than in the hepatectomy group (p<0.001). Larger tumors and vascular involvement in the hepatectomy group were significantly more frequent than in the ablative therapy group (p<0.001 and p=0.002, respectively). The multivariate Cox regression analysis indicated no significant difference either in the time to the first recurrence of tumor after surgery or in mortality between ablative therapy and hepatectomy. By making full use of various modalities in each specialty, the satisfactory HCC treatment could be achieved at this stage.
Keywords: Hepatocellularcarcinoma / Hepatectomy / Ablativetherapy
URI: http://hdl.handle.net/10069/9272
ISSN: 00016055
Relational Links: http://joi.jlc.jst.go.jp/JST.JSTAGE/amn/49.87
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 49, No. 3

Citable URI : http://hdl.handle.net/10069/9272

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