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An Angiotensin Receptor Blocker and Spironolactone Enabled A Withdrawal from Furosemide and KCl in A Patient with Pseudo-Bartter's Syndrome


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タイトル: An Angiotensin Receptor Blocker and Spironolactone Enabled A Withdrawal from Furosemide and KCl in A Patient with Pseudo-Bartter's Syndrome
著者: Ashizawa, Naoto / Fukae, Satoki / Tanaka, Kyoei / Suzuki, Nobuaki / Seto, Shinji / Yano, Katsusuke
発行日: 2004年 9月
引用: Acta medica Nagasakiensia. 2004, 49(3), p.107-109
抄録: A 30-year-old woman with pseudo-Bartter's syndrome was referred to our department because of hypokalemic symptoms caused by outrageous abuse of furosemide and by KCl infusion administered to compensate for it. As an attempt to break this vicious cycle, we first tried to change furosemide with azosemide, a long-lasting loop diuretics, to avoid acute excessive diuresis and excretion of potassium. Administration of losartan effectively attenuated the concentration of extremely activated plasma aldosterone. Administration of spironolactone reduced aldosterone breakthrough induced by losartan and the patient was released from both furosemide and KCl. Blocking renin-angiotensin-aldosterone system demonstrated to be an effective treatment for pseudo-Bartter's syndrome by the improvement of the total body potassium level which was decreased before treatment.
キーワード: Aldosteronebreakthrough / Angiotensinreceptorblocker / Furosemide / Pseudo-Bartter'ssyndrome / Totalbodypotassium
URI: http://hdl.handle.net/10069/9275
ISSN: 00016055
関連リンク : http://joi.jlc.jst.go.jp/JST.JSTAGE/amn/49.107
資料タイプ: Departmental Bulletin Paper
原稿種類: publisher
出現コレクション:Volume 49, No. 3

引用URI : http://hdl.handle.net/10069/9275

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