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Sensitive in vivo Assay System for Human Stem Cells Using NOD/SCID/γcnull mice


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Title: Sensitive in vivo Assay System for Human Stem Cells Using NOD/SCID/γcnull mice
Authors: Hiramatsu, Hidefumi / Fujino, Hisanori / Heike, Toshio / Ito, Mamoru / Nakahata, Tatsutoshi
Issue Date: Dec-2005
Citation: Acta medica Nagasakiensia. 2005, 50(supl.1), p.39-43
Abstract: Recent advances in stem cell research present us promising possibilities for regenerative medicine. However, investigation on human stem cells is behind from those of murine mostly due to the lack of appropriate analyzing systems. Our NOD/SCID/γcnull (NOG) mice model realized complete reconstitution of lympho-hematopoietic system as well as liver regeneration by human hematopoietic stem cell transplantation. This model will provide a versatile tool to investigate not only human hematopoietic system but also other human stem cell systems along with stem cell plasticity.
Keywords: NOD/SCID/γcnullmice / Hematopoieticstemcelltransplantation / Stemcellplasticity
URI: http://hdl.handle.net/10069/9310
ISSN: 00016055
Relational Links: http://joi.jlc.jst.go.jp/JST.JSTAGE/amn/50.S39
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 50, No. supl.1

Citable URI : http://hdl.handle.net/10069/9310

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